Monday, March 16, 2015
Bacteria Migrating to Breast May Cause Cancer
—-The other 200 posts—-
The readers of this blog are probably aware of my interest in the causes and related cures of diseases. Juxtaposition of recent research findings has made me reconsider the role of bacteria in breast cancer.
The Findings
- Lactation/breastfeeding lowers risk of breast cancer (improves path of normal mammary duct micro biome from nipple.)
- Tubal ligation lowers risk of ovarian cancer (eliminates path for bacteria from vagina.)
- Aspirin reduces pancreatic cancer (by reducing inflammation involved in the transition from bacterial infection to cancer.)
- Pancreatic and breast cancer risks are both dramatically increased by BRCA (tumor suppressor genes involved in 5% of breast cancer.)
- Bacteria are transported from gut to blood to breast to milk to infants. (Google entero-mammary bacterial circulation involving intestinal M cells and dendrocytes.)
Bacteria Have Access to Organs with Common Cancers
Serum or fluid flows from organs outward; liver to gall bladder to intestines, pancreas to intestines, prostate to urethra, ovary to fallopian tube to uterus to vagina. In each case there is also an related infection and inflammation associated with the backward path to the organ. Urinary tract infections can lead to prostatitis. Vaginitis can lead to pelvic inflammation, gastritis to stomach cancer, and intestinal infection/inflammation can result in pancreatitis. The theme seems to be that bacterial infections can cause inflammation that leads to cancer.
Bacterial Path to the Breast
Lactating women occasionally have bacteria that migrate back up milk ducts to cause mastitis, but this is not quite parallel to my other examples of bacterial movement, because women are not continually producing milk. There is, however, another path of bacteria to mammary tissue. Prior to birth, bacteria move from the maternal gut, through the blood (presumably in lymphocytes) and into mammary tissue. Subsequent nursing transports the bacteria to the infant to initiate the milk controlled gut flora unique to exclusively breastfed infants.
Monthly Transport of Bacteria to Breast
The menstrual cycle is an abbreviated ovulation, conception, gestation and birth, which suggests that just as in the normal prelude to lactation, there may also be monthly transport of gut bacteria to mammary tissue. These bacteria may also cause infection and inflammation, though they may not be sufficient to cause more than transient breast tenderness.
Healthy Gut Flora Means Healthy Breasts
I expect that many diseases in infants may be associated with the wrong bacteria being transported from maternal gut to breast to infant. Clearly, if the mother suffers from dysbiosis, which is very common, it may be difficult for the correct Lactobacilli and Bifidobacteria to be transported to mammary tissue. Transport of other bacteria may cause problems. Those problems may be severe as a consequence of menstrual cycles that don’t end in pregnancy, but rather end in infection, inflammation and breast cancer. It may all come down to gut flora. The difference between women who develop breast cancer and those that remain healthy may be the health of their gut flora. Breastfeeding, of course, reduces the risk of breast cancer, as well as improving infant gut flora. Formula is always a risk factor for infant health, because it attacks normal infant gut flora and promotes inflammation. Since many breast cancers naturally resolve, it may also be the case that a healthy immune system can reverse breast cancer and the health of the immune system is determined by the gut flora.
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